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About Eurofins CRL Cosmetics, LLC

Eurofins CRL Cosmetics provides a range of clinical safety and efficacy testing to the cosmetic, beauty products, personal care and pharmaceutical industries, with clinical expertise in the areas of dermatology, photobiology, ophthalmology, bioinstrumentation, microbiology, cosmetology, clinical trials, sun protection and associated services.

Locations

Forest

Laboratory

1080 Light Blvd Unit 101, Forest VA 24551, United States

Laboratory

Piscataway

Laboratory

371 Hoes Lane, Suites 100 New Jersey, Piscataway NJ 8854, United States

Laboratory

Austin

Laboratory

11212 Metric Boulevard, Austin TX 78758, United States

Laboratory

Winston-Salem

Laboratory

411 W 4th St., Winston-Salem NC 27101-2857, United States

Laboratory

Accreditations

Issuing Body Perry Johnson Laboratory Accreditation, Inc

Issuing Body Country UNITED STATES OF AMERICA

Issuing Body Website http://www.pjlabs.com/

About Eurofins | CRL

Clinical studies for your cosmetic, skincare and health products

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Welcome to Eurofins CRL, your trusted partner in clinical testing. 

 

Established in 1992, we stand as an ISO 9001:2015 and GCP compliant contract laboratory, operating at the forefront of clinical safety and efficacy testing.  We have a robust track record spanning more than two decades,  successfully completing over 20,000 clinical testing studies for 300+ businesses, including some of the world’s leading consumer products companies. Our state-of-the-art 22,000 square foot clinical testing facility, combined with our team of skilled professionals, ensures the highest standards in clinical studies and testing. With headquarters in central New Jersey and additional facilities in North Carolina, Virginia, and Texas, Eurofins CRL is dedicated to serving the cosmetic, beauty products, personal care, and pharmaceutical sectors.

Why Choose Eurofins CRL?

Collaborate with Eurofins CRL and experience uncompromising excellence in clinical trial management. Your success is our mission.

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Expertise

Benefit from our extensive experience in conducting studies for package stability/compatibility testing, Microbiology, Safety testing, anti-aging claims, SPF efficacy, and various cosmetic and personal care product categories

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Trained in Good Clinical Practice (ICH GCP and ISO 9001:2015) , they possess all the skills necessary for the success of your studies.

  • Doctors and specialists : dermatologists, ophthalmologists, pediatricians, gynecologists, etc.
  • Research technicians, nurses, beauty experts (hairdressers, beauticians, expert panelists)
  • Project managers, clinical research associates (CRAs)
  • Specialized support services : biostatistics, R&D, regulations, quality assurance, scientific communication


Each study is led by a dedicated Project Manager who will support you from the implementation of the protocol to the sending of the final report.

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Client-centric Approach

Discover the Eurofins CRL difference, a personalized approach to clinical testing.

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Our Mission: To be the laboratory of choice for in vivo clinical testing, and we achieve this by working with each client individually to develop a customized safety and efficacy testing program. Our committed management and staff collaborate closely, ensuring that we align with your study objectives while respecting your budgetary constraints.

Global Reputation: Eurofins CRL has established long-term contracts with major consumer products companies globally, earning a reputation for excellence in clinical studies and testing.

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Comprehensive Database

Our database boasts over 35,000 panelists, allowing us to design clinical trials with multiple study-related variables, ensuring precision in your testing programs.

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We offer representative panels tailored to the objectives, including:

  • All ages: from infants to seniors
  • Ethnic diversity
  • All skin types: normal, sensitive, atopic-prone skin…
  • All characteristics affecting the skin, hair, mucous membranes or well-being
  • All climates
  • All lifestyles, to reflect the reality of consumers

This diversity allows for a precise evaluation of the tolerance, safety, and effectiveness of products

Our areas of expertise

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Clinical & Efficacy Testing

 

Eurofins CRL offers tests that comply with regulatory requirements: safety, efficacy, and consumer tests, conducted under standardized conditions or according to normal conditions of use.
 
Our expertise extends across various domains, including: 

  • Dermatology 
  • Photobiology & SPF Testing
  • Ophthalmology
  • Bioinstrumentation (Efficacy & Claim Substantiation)
  • Microbiology
  • Cosmetology
  • Custom Clinical Trials
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Investigational New Drug (IND) & Aesthetics

 

Eurofins CRL IND and Aesthetics offers tests that comply with IRB and regulatory requirements.
 
Our expertise extends across various domains, including:

  • Topical Medications and Products
  • Oral Prescription and Over-The-Counter Drugs
  • Health and Beauty Aids
  • Medical Devices

Contact Us

Our specialist teams are ready to listen to you and work with you to design a study solution tailored to your objectives and constraints.

 

📩 Contact our experts

Clinical Services

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At Eurofins CRL, we understand the importance of thorough pre-market assessments for consumer and personal care products, including cosmetics.

Our diverse array of safety and clinical studies delivers cutting-edge insights, fostering smart product development and ensuring compliance with industry standards.

We offer customizable study protocols tailored to meet your specific client and product requirements, specializing in expedited safety assessments. Our streamlined approach ensures efficient information gathering, enabling cost-effective decision-making in product development.

Safety-In-Use, Efficacy, and Claims Substantiation

In vitro and In vivo

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Safety-in-Use Testing

Eurofins CRL's Safety-in-Use (SIU) Test is a crucial study designed to evaluate your product's potential to cause skin irritation under real-life conditions. This comprehensive test provides essential insights for both normal and exaggerated use scenarios, making it a vital component of cosmetic and personal care product testing.

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Comprehensive Assessment for all Skin Types

Often recommended as a follow-up to the Human Repeated Insult Patch Test (HRIPT), the SIU test assesses the likelihood of skin irritation, including individuals with sensitive skin. To ensure reliable and representative results, we recommend a minimum of 30 subjects, with larger participant groups yielding even greater accuracy.

For baby or children's products, we can include age-appropriate subjects with Institutional Review Board (IRB) approval, ensuring the safety of your products for all target demographics.

Rigorous Testing Procedure for Accurate Results

Eurofins CRL’s SIU testing process is designed to provide accurate and reliable results. Simply provide individual units of your product, and our experienced staff will handle the rest. At the baseline visit, a dermatologist or trained professional will examine the intended product use area, ensuring direct contact with the skin. Test sites are graded for erythema, edema, and dryness, providing valuable insights into potential skin reactions.

Subjects receive test products, detailed usage instructions, and a daily diary to record each use. After the study period, subjects return for a final evaluation, which includes dermal examinations and recording of erythema, edema, and dryness levels, ensuring a comprehensive assessment of skin health.

Expert Analysis & Reporting

Our Principal Investigator meticulously reviews all results and reported adverse events, focusing on identifying potential irritants or allergens. Mild dryness in a few subjects is generally not clinically significant. However, signs of erythema, edema, or rashes may indicate irritation or allergy, warranting further to confirm the relationship to the test product.

Make Informed Decisions with Eurofins CRL's SIU Testing

Eurofins CRL's Safety-in-Use (SIU) testing provides you with the data you need to make informed decisions about your product's safety. Our expert team delivers reliable, accurate results, giving you the confidence to bring your cosmetic or personal care products to market.

Trust Eurofins CRL's SIU testing to prioritize your product's safety and give you a competitive edge in the industry. Contact us today to learn more about how we can help you ensure your product's safety and success.

Testing Categories

  • Ophthalmology
  • Gynecology
  • Dermatology
  • Pediatric
  • Dental
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Human Repeated Insult Patch Test (HRIPT)

Human Repeated Insult Patch Testing (HRIPT) is a critical 6‑week study that assesses the sensitization and irritation potential of materials used in cosmetics, toiletries, drugs, devices, and personal care products by repeatedly exposing participants to the test material to reveal any sensitization or irritant reactions, ensuring product safety and skin compatibility.

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Flexible HRIPT Testing Procedure

Our HRIPT services offer the flexibility to test your products alongside those of other companies or exclusively focus on your own formulations. We recommend testing with at least 100 subjects for robust results, however we can accommodate panels ranging from 50 to 200 participants. Our 24-hour exposure protocol involves applying the test product to occlusive or semi-occlusive patches on the upper back.

During the 3-week Induction Phase, subjects undergo regular patch applications and evaluations. Following a 14-day rest period, the Challenge Phase begins, where test products are applied to a virgin site on the lower back. Evaluations are conducted at 24, 48, 72, and, if necessary, 96 hours post-patch removal.

Comprehensive HRIPT Results and Reporting

Eurofins CRL’s HRIPT studies provide a comprehensive picture of your product's sensitization and irritation potential. Minimal, transient reactions during the Induction or Challenge Phases, unless observed in more than a few subjects, are generally not clinically significant. Sensitization reactions, characterized by intense erythema, edema, and itching, may occur.

We provide unaudited topline results within 1 week of study completion, followed by a detailed final report approximately 2 weeks post study. This report includes a thorough analysis of the results, helping you to make informed decisions about your product's safety and compatibility with human skin.

Ensure the safety and efficacy of your cosmetics, toiletries, drugs, and personal care products with Eurofins CRL expert HRIPT services. Partner with us to gain valuable insights into sensitization and irritation potential, and confidently bring your products to market.

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Ophthalmic Safety-In-Use

Our Ophthalmic Safety‑In‑Use (Op SIU) test provides in‑depth insights into how eye cosmetics and hair care formulations affect ocular health by evaluating whether products used on the face or eye area may cause discomfort, irritation, or harm to the eyes, eyelids, or surrounding skin during application or daily use.

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Essential for Eye Cosmetics and Eye-Contacting Products

Op SIU testing is particularly crucial for eye cosmetics and other cosmetic products that may come into contact with the eyes, as these formulations can potentially trigger allergic reactions, eyelid irritation, or eye infections. For a comprehensive analysis, Op SIU can be paired with Dermal Safety-in-Use (Op/Derm SIU) for products such as foundations, moisturizers, sunscreens, shampoos, or conditioners.

To ensure reliable and representative results, we recommend a study group of at least 30 subjects, including individuals who wear contact lenses and those with self-perceived sensitive eyes.

Rigorous Testing Procedure for Accurate Results

Our Op SIU testing process begins with the submission of individual units of your cosmetic products, which our team assigns with study and subject numbers. During the initial visit, subjects undergo visual acuity checks and comprehensive eye examinations to detect any pre-existing inflammation, abnormalities, allergic reactions, or eye infections. We also assess subjective irritation, lacrimation (tearing), and the conditions for wearers of contact lenses. Qualified subjects then receive the test products, along with detailed usage instructions and a daily diary to monitor each application.

After the designated product use period, a comprehensive evaluation is conducted, including visual acuity assessments, changes in contact lens condition, and subjective reports of irritation.

In-Depth Analysis and Comprehensive Reporting

All results undergo thorough examination by our Principal Investigator, focusing on ocular and dermal evaluations, and any reported adverse events, including potential reactions to the cosmetic products under evaluation.

While mild inflammation of the conjunctivae may be observed, it is typically not clinically significant. However, pronounced inflammation, corneal abnormalities, or subjective discomfort may indicate an adverse reaction to the test product, warranting further investigation.

Actionable Results for Product Optimization

For your convenience, preliminary topline results can be provided verbally or in writing about one to two weeks after the study's completion. A detailed, audited final report will follow shortly thereafter, providing actionable insights to guide product optimization and enhance safety, ensuring your formulations meet the highest standards of ocular safety.

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Acnegenicity/Comedogenicity

Our Acnegenicity/Comedogenicity Study empowers you to substantiate this claim with scientific evidence to support consumer confidence and market success while also evaluating the potential for skin irritation when paired with a Safety‑in‑Use assessment.

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Reliable Results

  • We leverage a minimum of 30 subjects (increased numbers enhance reliability) over a 4–6-week period with daily (or more frequent) facial applications.
  • Ideal for pre-market assessment and consumer safety claims

Streamlined Study Process

Our streamlined study provides an evidence-backed and proven process. The process includes:

  • Product Submission: Provide individual units sufficient for each subject's needs.
    Skin Health Assessment: Our team meticulously evaluates facial skin health across diverse skin types during the initial visit.
  • Lesion Count & Product Application: Dermatologists or trained staff conduct acne lesion counts on suitable subjects (normal to oily or acne-prone skin). They then receive the test product, usage instructions, and a daily diary for recording applications.
  • Final Evaluation: Following the study period, subjects return for a final assessment, including a repeat acne lesion count and recording.
  • Optional Consumer Feedback: An optional final questionnaire gathers valuable insights on the consumer's experience with the product.

Clear and Actionable Reporting

Upon completion, we analyze changes in lesion counts to support your non-comedogenic and non-acnegenic claims. If no significant increase in non-inflammatory or total lesions occurs, the evidence strengthens your claims. 

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Facial Sting Study

Eurofins CRL's Facial Sting Test is a comprehensive one‑day clinical study that evaluates a product’s potential to induce a stinging response across various skin types, with a focus on identifying sensitive‑skin subjects to provide valuable insights into overall skin comfort.

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Comprehensive Results and Reporting

Stinging intensity scores are compared to saline and the pre-screening lactic acid stinging score, providing insights into potential allergic reactions and skin sensitivities. Statistical comparisons offer a comprehensive understanding of your product's impact on different skin types and conditions. Topline results, available verbally or in writing post-analysis, pave the way for a detailed final report, ensuring compliance with study protocol and industry standards.

Eurofins CRL's Facial Sting Test not only helps you understand your product's skin comfort potential but also provides valuable data for product development and marketing. Our expert team is dedicated to delivering accurate, reliable results that help you make informed decisions and bring your product to market with confidence.

Trust Eurofins CRL to unveil your product's true potential and set you apart from the competition.

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Gynecology Studies

Eurofins CRL provides gynecological product research, where safety and efficacy studies are meticulously conducted under the supervision of Board Certified Gynecologists.

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Eurofins CRL provides gynecology studies tailored to the assessment of women's health care and feminine hygiene products, including:

  • Tampons
  • Personal lubricants
  • Vaginal suppositories
  • Sanitary napkins
  • Vaginal contraceptives
  • Bubble bath and other bathing products
  • Incontinence products
  • Feminine hygiene sprays and douches
  • Cleansing wipes

Claim Support and Study Types

Our dedicated team, including Registered Nurses and a Board-certified Gynecologist, conducts studies to support various claims, such as:

  • Irritation Potential
  • Vaginal Drying
  • Vaginal pH
  • Dissolution Studies
  • Moisturization
  • Fiber Retention (tampon products)

We offer a range of study types, including Safety Assessments, Efficacy Evaluations, and Consumer Opinion Studies, to meet your specific objectives.

Our Expertise

Eurofins CRL has a dedicated team, including Registered Nurses and a Board-certified Gynecologist, ensuring the highest standards in conducting and overseeing gynecology studies. Our professionals offer tailored advice on study designs aligned with your product and its support claims.

Study Types

  • Safety Assessments: Tailored Safety-in-Use studies may include external or internal examinations, as well as pre- and post-use pH measurements.
  • Efficacy Evaluations: Customized studies meet sponsor specific objectives, involving measurements like pre- and post-use weights or subject questionnaires.
  • Consumer Opinion Studies: Gain valuable insights into consumer perspectives about your products.

Statistical Relevance

For Safety-in-Use studies, we recommend a minimum of 30 subjects for statistical relevance. However, our commitment to reliability encourages testing with more subjects to enhance result accuracy.

Subject-centric Approach

Ensure an efficient participant experience by providing labeled individual units of the test product. Subjects receive clear instructions, a daily diary, and return for a final examination and questionnaire completion.

Results Reporting

Experience immediate insights with unaudited topline results, available verbally or in writing. For a thorough understanding, all study results are delivered in an audited final report.

Choose Eurofins CRL for tailored gynecology research solutions that improve the safety, efficacy, and consumer perception of your women's health care and feminine hygiene products.

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Dental Studies

Eurofins CRL provides dental product research, where safety and efficacy studies are meticulously conducted under the supervision of Registered Dental Hygienists and/or licensed Dentists.
 

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Comprehensive Dental Product Research Services

Eurofins CRL provides comprehensive dental product research services, conducting safety and efficacy studies under the supervision of Registered Dental Hygienists and licensed Dentists. Our expertise spans a wide range of dental products.

Capabilities include:

  • Oral Mouth Rinse Studies
  • Tooth Whitening
  • Toothpaste Studies (Anti-Caries, Anti-Tartar, Anti-Plaque, Anti-Gingivitis, Teeth Whitening, Product Safety)
  • Denture Rinses
  • Toothbrush Evaluations
  • Sensitization Studies
  • Pre-Brushing Mouth Rinses
  • Dental Floss

Tailored Studies for Your Specific Objectives

Our seasoned professionals work closely with you to design studies that align with your unique requirements and claims. Examples of our studies include:

  • Safety-in-Use assessments
  • Tooth Whitening Efficacy evaluations
  • Denture Adhesive Safety and Efficacy analyses

We offer flexible study durations and clinic visits based on your product's instructions and intended claims, ensuring a comprehensive evaluation of your dental product.

Comprehensive Examination Protocols

  • Safety-in-Use Studies: Pre- and post-use visual examinations of the buccal mucosa and tongue
  • Tooth Whitening Efficacy Studies: VITA® Shade Guide for grading tooth shade before and after product applications
  • Denture Adhesive Studies: Pre- and post-use visual examinations, subjective and/or objective assessments of removal force

Flexible Study Duration and Visits

The duration and clinic visits vary based on your product's instructions and intended claims, ensuring flexibility and adaptability in study design. Our approach ensures studies are aligned with your unique requirements, delivering comprehensive assessments for dental products.

Subject-centric Approach and Results Reporting

We prioritize the subject experience, providing daily diaries and clear instructions for product use. Benefit from unaudited topline results for immediate insights, followed by a comprehensive audited final report.

Partner with Eurofins CRL for tailored dental product research solutions that elevate the performance and effectiveness of your products.

Results Reporting

Benefit from unaudited topline results for immediate insights, delivered verbally or in writing, providing timely feedback on study outcomes. For a comprehensive understanding, all study results are provided in an audited final report, ensuring accuracy and reliability in dental product evaluations.

Eurofins CRL offers precision, expertise, and excellence in dental product studies. Partner with us for tailored research solutions that elevate the performance and effectiveness of your dental products.

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Cosmetology Testing

Our cosmetology testing services are carried out by licensed, highly experienced cosmetologists who thoroughly assess a wide range of product attributes, provide insights into both existing and emerging offerings, and conduct rigorous safety and efficacy testing for hair care appliances to ensure complete evaluation of product performance and compliance.

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Fully Equipped On-Site Salon for Realistic Testing

Our state-of-the-art facility features a fully equipped, on-site salon supervised by a full-time staff of licensed and experienced cosmetologists. Our salon can accommodate panels of any size, ensuring comprehensive assessments tailored to your specific needs.

Hair Care Product Testing

Our hair care cosmetology services cover a wide range of evaluations, including:

  • Shampoo/Conditioner
  • Styling Aids (volumizing, reducing oiliness, improving shine, anti-frizz, improving hair’s bounce, etc.)
  • Scalp Treatments
  • Ethnic Hair Treatments (Relaxers, etc)
  • Half-head or Full-head evaluations
  • Hair Color
  • Dandruff Studies
  • Hair Straighteners
  • Tangle, Static, Wet and Dry Combing, Shine, etc.
  • Permanent Wave
  • Hair Growth or Strengthener Treatments

Nail Care Product Testing

Our nail care cosmetology services include testing and evaluations for:

  • Nail Enamel
  • Gloss, Shine
  • Wear Properties and Durability (chipping, flaking, etc.)
  • Dry Time
  • Application Qualities
  • Cosmetologist Evaluations and Consumer Perceptions
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Consumer Research

Our consumer research studies are meticulously designed to gather invaluable insights on various aspects, including product aesthetics, efficacy, marketing potential, and ease of use. By leveraging these consumer perspectives, you can elevate your product and make informed decisions that resonate with your target audience.

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Tailored Studies for Specific Needs

We understand that every product and brand have unique requirements. That's why Eurofins CRL offers tailored consumer research studies, ensuring you obtain the specific information needed to enhance your product. From acceptance to efficacy, our studies uncover valuable insights that drive product refinement and optimization.

The Consumer Research Journey

  • Survey Capture Procedure
    • Design custom studies based on your objectives, utilizing questionnaire responses for statistical relevance.
    • Enroll a recommended minimum of 30 subjects, ensuring proper insights.
  • Procedure
    • Implement studies under normal use conditions, spanning single-use assessments or extended usage over a number of weeks.
    • Subjects receive labeled test products, usage instructions, and daily diaries for comprehensive feedback.
  • Questionnaire Design
    • Collaborate with Eurofins CRL experts to create effective questionnaires, maintaining subject focus with a maximum of 25 questions.
    • Utilize computerized programs for direct entry and efficient response tabulation.
  • Interpretation & Reporting
    • Receive a detailed final report with a tabulation of responses, showcasing subject choices and percentages.
    • Optional statistical analysis, including Z-tests, highlights the significance between positive and negative responses.

Claims/Efficacy Testing

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Claims / Bioinstrumentation

Standard and custom protocols deliver objective clinical measurements for personal care and cosmetic product claim support.

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Our experience in this facet of clinical testing is considerable. Our equipment is truly advanced. Studies are conducted in a controlled environment by highly skilled and thoroughly trained technicians. Standard protocols have been developed to substantiate a wide variety of cosmetic and personal care product claims. Custom protocols can be developed to support your specific test requirements. In addition, we have the technical expertise to thoroughly interpret the data and provide you with reports suitable for both your technical and marketing needs.

Capabilities include:

  • Anti-aging Claims Support
  • Moisturization & Skin Hydration
  • Skin Texture
  • Cell Turnover/Cell Renewal
  • Skin Elasticity, Extensibility, & Firmness
  • TEWL
  • VISIA-CR
  • Clarity System
  • Skin Luminosity, Skin Color/Skin Tone, Evenness of Color
  • Video Microscopy of the Skin & Skin Structures
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Photobiology & SPF Testing Services

Photobiology is the scientific study of the interactions between ultraviolet (UV) radiation and the skin. For cosmetic and personal care brands, this science is the foundation of sun protection, providing the framework for developing effective products and substantiating their performance claims. In a competitive market governed by stringent global regulations, scientifically rigorous SPF testing is not just a quality control measure it is a critical component of a successful product launch.

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Comprehensive Sunscreen Testing Solutions

Our capabilities cover the full spectrum of modern sun care SPF testing, providing the precise data needed to support your product’s efficacy, safety, and marketing claims. Each service is conducted according to the highest global standards to ensure your results are accurate, repeatable, and ready for regulatory submission.

  • SPF Determination (UVB Protection): We provide precise Sun Protection Factor (SPF) determination, the global standard for UVB protection. Our clinical studies adhere to the gold-standard ISO 24444:2019 methodology as well as the requirements of the FDA Monograph, ensuring your product's primary efficacy claim is indisputable. We provide expert guidance on the science of SPF, a measure of protection against the amount of solar energy, not simply time in the sun.
  • Broad-Spectrum UVA/UVB Protection Assessment: A truly effective sunscreen must protect against both burning UVB rays and ageing UVA rays. However, the global regulatory landscape for UVA testing is highly fragmented. We offer a unified solution, with expertise in all major international standards. Whether you need ISO 24443 (in vitro UVAPF) for the European "UVA in a circle" logo, ISO 24442 (in vivo PPD) for the Asian PA++++ rating system, or the FDA's Critical Wavelength test for a US "Broad-Spectrum" claim, we provide the specific data required for each market.
  • Water Resistance & Specialized Claims: To stand out in a crowded market, brands require data to support specialized claims. We conduct water resistance testing for both 40-minute and 80-minute claims according to ISO 16217 & ISO 18861 protocols. We also offer testing to substantiate other valuable claims, such as sweat resistance, sand resistance, and effective application on wet skin.

State-of-the-Art Testing Facilities

Our commitment to accuracy is reflected in our state-of-the-art facilities and instrumentation. Our laboratories are equipped with advanced solar simulators, including Xenon Arc lamps, which are meticulously calibrated to meet the strict spectral output requirements defined by ISO and other global standards. This ensures that the UV radiation used in our tests precisely mimics natural sunlight. Beyond technology, our greatest asset is our expert team.

Our seasoned scientists, clinical technicians, and regulatory specialists do more than just generate data they provide consultative support, helping you interpret complex results and navigate the path to compliance.

Industries & Applications

Our photobiology expertise serves a range of industries where sun protection is a critical factor for product performance and safety.

  • Cosmetics and personal care
  • Pharmaceuticals (OTC drugs)
  • Textiles and materials (UPF testing)
  • Research and development
In Vivo

In vivo sunscreen testing delivers the gold‑standard proof for SPF, UVA, and water‑resistance claims, ensuring regulatory compliance and real‑world performance on human skin.

In Vitro

This service provides fast, reliable in vitro photobiology testing using ISO‑aligned methods to assess SPF, UVA, and related protection, helping teams evaluate formulas and support claim development.

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Microbiology & Stability Testing

Our GCP-compliant facilities and FDA-recognized expertise make sure your products meet global standards of safety, quality, and compliance. 

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Eurofins CRL Research Labs is a leading microbiology testing lab serving the cosmetic, personal care, and pharmaceutical industries. Our GCP-compliant facilities and FDA-recognized expertise make sure your products meet global standards of safety, quality, and compliance. 

We support R&D scientists, product formulators, and quality teams with reliable data, from validating new preservative systems to running antimicrobial efficacy tests for NDA submissions.

1. GCP-Compliant Topical Antimicrobial Expertise
Our specialized lab in Texas focuses on the topical antimicrobial market. We deliver the antimicrobial effectiveness test and cosmetic microbiological tests required for OTC and pharmaceutical products. All testing follows GCP standards, giving you trusted results for regulatory submissions.

2 . Global Regulatory Partnership
We act as your regulatory partner, guiding you through FDA requirements (including MoCRA), Health Canada, and the European Commission. With services like preservative efficacy testing and USP for preservative efficacy compliance, we help you achieve faster approval and global market access.

3. Comprehensive QC Solutions
We provide a full suite of quality control services at every stage of your product’s lifecycle. From preservative efficacy testing and raw material checks to final batch release, our solutions ensure product safety, stability, and consistency.

4. Custom Method Development
Our scientific team develops and validates custom testing methods for unique formulations. Whether you need specialized Preservative Efficacy Testing, antimicrobial efficacy test protocols, or advanced antimicrobial effectiveness test data, we design methods that deliver accurate, reliable results.

Understanding Microbiological Testing: Why It's Essential for Your Product

Microbiological testing is the scientific analysis of raw materials, in-process samples, and finished products for the presence and quantity of microorganisms such as bacteria, yeast, and mold. For the cosmetic, personal care, and pharmaceutical sectors, this testing is not merely a quality control measure; it is a fundamental requirement for commercial success and consumer safety. A robust microbiological testing program is built on four essential pillars that directly impact your product's viability in the market.

1. Ensuring Consumer Safety
The main goal of cosmetic microbiological testing is to keep consumers safe. Harmful microbes such as Staphylococcus aureus, Pseudomonas aeruginosa, or Escherichia coli can cause skin infections, allergic reactions, and serious health problems. Under FDA rules, any product contaminated with these organisms is considered adulterated. Rigorous antimicrobial efficacy tests confirm that your product is free from dangerous microbes before it reaches the market.

2. Guaranteeing Product Stability & Shelf-Life
Uncontrolled microbial growth can spoil products, changing their color, smell, and texture, and breaking down active ingredients. This makes products ineffective and unsafe. Preservative Efficacy Testing (PET), also called a preservative challenge test, proves that your preservative system protects the formula throughout its shelf-life and use period. Following the USP for preservative efficacy standards helps prevent costly product recalls while ensuring long-term stability.

3. Substantiating Marketing Claims
In today’s competitive market, strong claims need solid proof. Studies like antimicrobial effectiveness tests and Time-Kill studies provide quantitative data to support statements such as “kills 99.9% of germs in 15 seconds.” This kind of evidence not only builds consumer trust but also sets your product apart from competitors.

4. Achieving Global Regulatory Compliance
Microbiological testing is essential for regulatory approval worldwide. In the European Union, for example, preservative efficacy testing results are required in the Cosmetic Product Safety Report (CPSR) under Regulation (EC) No 1223/2009. In the United States, the Modernization of Cosmetics Regulation Act (MoCRA) requires compliance with Good Manufacturing Practices (GMP), where cosmetic microbiological testing and quality control are critical. Meeting these standards ensures smoother access to global markets.

A Full Spectrum of Microbiology Testing Services

Eurofins CRL provides a comprehensive portfolio of microbiology testing services, from foundational quality control assays to highly specialized efficacy studies. Our capabilities are structured to support your product from initial formulation through to post-market surveillance, ensuring quality and compliance at every step.

Specialized Topical Antimicrobial Efficacy Testing

Our core area of specialization lies in the efficacy testing of topical antimicrobial products. Operating from a dedicated, GCP-compliant facility, we provide the highest quality data to support regulatory submissions for over-the-counter (OTC) drugs and pharmaceutical products. Our services are designed to validate the effectiveness of healthcare personnel's hand washes, surgical scrubs, hand sanitisers, and other antiseptic formulations for global markets.

Classical Microbiology for Quality Control & Batch Release

These foundational services are the bedrock of a robust Good Manufacturing Practice (GMP) quality program. We perform essential tests required for the routine quality control of cosmetic, personal care, and non-sterile pharmaceutical products. This includes preservative efficacy testing or antimicrobial effectiveness test (PET/AET) to ensure product stability, Microbial Limits Testing (MLT) to confirm batch quality before release, and Time-Kill studies to substantiate germicidal claims.

Tailored Microbiology Solutions for Your Industry

We understand that each industry faces unique microbiological challenges and regulatory landscapes. Our services are tailored to address the specific needs of the cosmetic, pharmaceutical, and OTC sectors, providing expert guidance and compliant testing solutions.

Cosmetic & Personal Care Testing
The cosmetic industry is currently navigating the "clean beauty" movement, which presents a significant challenge for formulators: creating products that are both safe and align with consumer demand for "natural" ingredients and shorter ingredient lists. This trend often restricts the use of traditional, highly effective preservatives, making robust preservative efficacy tests more critical than ever. 

We partner with formulators to validate alternative preservative systems, "hurdle technology" approaches, and multifunctional ingredients, ensuring products are effectively protected against microbial contamination while meeting market expectations. 

Our expertise extends to ensuring compliance with key global regulations, including the FDA's Modernization of Cosmetics Regulation Act (MoCRA), the EU's Regulation (EC) 1223/2009.

Pharmaceutical & OTC Microbiology
The pharmaceutical and OTC sectors operate under the most stringent regulatory requirements. Our services are performed in compliance with current Good Manufacturing Practices (GMP) to ensure the highest level of data integrity. We specialize in providing the critical data needed for regulatory submissions, including New Drug Applications (NDA). 

Our expertise includes sterility assurance testing and the rigorous process of method validation, which is essential to demonstrate that a testing procedure is suitable for a specific product matrix, a fundamental requirement for regulatory bodies.

Our Suite of Topical Antimicrobial Testing Standards

Healthcare Personnel Hand Wash (ASTM E1174, EN 1499)

These standards evaluate rinse-off antiseptic soaps and washes used in healthcare and food service environments.

Hygienic Hand Rub & Sanitizers (EN 1500, ASTM E2755)

We provide efficacy testing for alcohol-based and other leave-on hand rub formulations according to the key standards required for market access in the U.S. and Europe.

Surgical Scrub Evaluation (ASTM E1115)

ASTM E1115 is a rigorous antimicrobial efficacy test assessing surgical scrubs for immediate and sustained microbial reduction in critical care settings.

Specialized & Screening Methods (Finger Pad, CHG Compatibility)

Beyond compendial methods, we offer specialized studies—finger pad screening, persistent efficacy testing, and CHG compatibility—tailored to healthcare product requirements.

Preservative Efficacy Testing (PET/AET / Challenge Test)

Evaluates the ability of a product’s preservative system to resist microbial contamination throughout its shelf life and consumer use. Critical for water-based cosmetics, lotions, & pharmaceuticals.

Microbial Limits Testing (MLT)

Quantifies the total bioburden and confirms the absence of specific objectionable organisms in finished goods. Ensures compliance with pharmacopeial microbiological quality standards.

Time-Kill & Rapid Germicidal Activity Studies (ASTM)

Evaluates how quickly and effectively antimicrobial agents kill or inhibit microorganisms commonly used to substantiate rapid-kill or “kills 99.9% in seconds” claims.

Zone of Inhibition Testing

Assesses antimicrobial activity by measuring the inhibition zone created by active ingredients or formulations against targeted microorganisms.

Minimum Inhibitory Concentration (MIC) & Minimum Bactericidal Concentration (MBC)

Determines the lowest concentration of an antimicrobial that prevents visible growth or kills a specified organism, essential for research and product optimisation.

Surface Swab & Environmental Testing

Validates the cleanliness of manufacturing environments and surfaces to support GMP compliance and contamination control programs.

Water Testing

Assesses the microbiological quality of process and purified water used in manufacturing, ensuring compliance with USP and ISO standards.

Do you have a study project?

Our specialist teams are ready to listen to you and work with you to design a study solution tailored to your objectives and constraints.

📩 Contact our experts

Investigational New Drug (IND) & Aesthetics

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Our experts have partnered with a wide range of sponsors and CROs, giving us extensive experience conducting Phase I–IV clinical trials. This background includes successful participation across numerous therapeutic areas, supported by rigorous scientific and operational expertise.

Testing Capabilities

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Therapeutic

Eurofins CRL provides comprehensive clinical expertise across a wide range of dermatologic and therapeutic conditions, supporting product development from early research through regulatory‑ready validation with scientifically rigorous, patient‑focused testing.

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We provide comprehensive testing for:

  • Acne
  • Actinic Keratosis
  • Aging Skin 
  • Alopecia
  • Atopic Dermatitis
  • Basal Cell Carcinoma
  • Bioequivalence
  • Cellulite
  • Contact Dermatitis
  • Corns, Calluses, Bunions
  • Dandruff
  • Eczema
  • Facial Hyperpigmentation
  • Hair Removal
  • Healthy Skin
  • Hyperlipidemia
  • Morton’s Neuroma
  • Onychomycosis
  • Neurofibromatosis
  • Otitis Externa
  • Otitis Media
  • Photoaging
  • Pseudofolliculitis Barbae (PFB)
  • Psoriasis
  • Rosacea
  • Seborrheic Keratosis
  • Solar Lentigines
  • Squamous Cell Carcinoma
  • Tinea Cruris
  • Tinea Pedis
  • Tinea Versicolor
  • Vitilligo
  • Warts
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Dermal Safety Testing

Dermal safety testing at Eurofins CRL evaluates products for irritation, sensitization, and overall skin compatibility. 

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We provide comprehensive testing for:

Acute Irritation

Assesses immediate skin or eye irritation following a single exposure to evaluate short‑term safety.

Contact Irritation

Evaluates localized skin irritation from repeated product contact to ensure user tolerability.

Contact Sensitization

Determines potential to cause allergic skin reactions after repeated exposure.

Cumulative Irritation

Measures irritation over repeated use to assess long‑term skin compatibility.

Injectable Fillers

Evaluates safety, tolerability, and local tissue response for dermal filler products.

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Device Studies

Device studies at Eurofins CRL evaluate the safety, performance, and user experience of a wide range of consumer and medical devices. 

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We provide comprehensive testing for:

Alopecia Comb

Evaluates comb devices for safety, scalp tolerance, and user ease in managing hair loss conditions.

Compression Sleeves

Assesses fit, comfort, and performance to support circulation, recovery, and therapeutic effectiveness.

Laser Safety

Validates device safety, output, and user protection to ensure compliance with laser use standards.

Shaving Equipment

Tests performance, skin compatibility, and ease of use for effective, irritation‑minimized shaving.

Shoe Inserts

Evaluates comfort, support, and durability to enhance foot health and user mobility in daily use.

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Dermal & Biopsy Procedures

Eurofins CRL offers a wide range of specialized clinical procedures to support product evaluation, safety, and performance. 

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We are able to perform Biopsy Procedures for:

  • Acne
  • Aging Skin
  • Blackheads
  • Hair Follicle
  • Healthy Skin
  • Post UV Exposure
  • Pseudofolliculitis Barbae (PFB)
  • UV Exposure

We have the capability to perform the following:

  • Cup scrubs
  • Delivery Systems
  • ECG
  • Hair Follicle Sampling
  • KOH Diagnostics
  • PK Sampling
  • Phlebotomy
  • Sebum Sampling
  • Swabs
  • Tape Stripping
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Post Marketing

Post‑marketing research at Eurofins CRL helps ensure products perform as intended in real‑world use.
 

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Over-the-Counter Label Comprehension

Evaluates how well consumers understand OTC labels, directions, and warnings to ensure safe, effective product use.

Qualitative Interviews

In-depth interviews capture user perceptions, behaviors, and experiences to inform product performance and positioning.

Taste Tests

Assesses flavor, texture, and overall acceptability to optimize consumer experience and product preference.

Do you have a study project?

Our specialist teams are ready to listen to you and work with you to design a study solution tailored to your objectives and constraints.

📩 Contact our experts

Our locations

Details of our Eurofins CRL locations

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Eurofins CRL New Jersey

Address: 371 Hoes Lane, Suite 100, Piscataway, NJ 08854, USA

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Eurofins CRL North Carolina

Address: 411 W 4th St Suite 100, Winston-Salem, NC 27101, USA

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Eurofins CRL Texas

Address: 11212 Metric Blvd., Suite 500, Austin, TX 78758, USA

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Eurofins CRL Virginia

Address: 1080 Light Blvd, Suite 201, Forest, VA 24551, USA
 

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Quality

Our Accrediations

Eurofins CRL New Jersey

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  • ISO 9001:2015
  • GCP compliant

Eurofins CRL North Carolina

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  • ISO 9001:2015
  • GCP compliant

Eurofins CRL Virginia

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  • CLIA Certification

Eurofins CRL Texas

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  • ISO 9001:2015
  • GCP Compliant Facility
  • GLP Compliant Facility